Characterization of lymphocytic choriomeningitis virus-binding protein(s): a candidate cellular receptor for the virus
نویسندگان
چکیده
منابع مشابه
Lymphocytic Choriomeningitis Virus
There has been an upsurge of interest in lymphocytic choriomeningitis virus (LCMV) as a human pathogen and specifically as an underdiagnosed congenital infection (1,2). LCMV is a member of the Arenaviridae family of viruses. Arenaviruses have a complex life cycle involving chronic infection and shedding of the virus in rodents and episodic infections in humans (3,4). Six of the arenaviruses (La...
متن کاملCharacterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein
RNA-dependent RNA polymerases (RdRps) play a key role in the life cycle of RNA viruses and impact their immunobiology. The arenavirus lymphocytic choriomeningitis virus (LCMV) strain Clone 13 provides a benchmark model for studying chronic infection. A major genetic determinant for its ability to persist maps to a single amino acid exchange in the viral L protein, which exhibits RdRp activity, ...
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Studies on Eaton PPLO Pneumonia ELLI JANSSON, 0. WAGER, R. STENSTROM, E. KLEMOLA, AND P. FORSSELL ... ... ... ... 142 Sensitivities of Colonies and Suspensions of Actinomyces Israelii to Penicillins, Tetracyclines, and Erythromycin G. C. BLAKE ... ... ... ... 145 Comparison of Ampicillin and Chloramphenicol in Treatment of Paratyphoid Fever R. A. SLEET, G. SANGSTER, AND J. MCC. MURDOCH ... ... ...
متن کاملNonneutralizing antibodies binding to the surface glycoprotein of lymphocytic choriomeningitis virus reduce early virus spread
The biological relevance of nonneutralizing antibodies elicited early after infection with noncytopathic persistence-prone viruses is unclear. We demonstrate that cytotoxic T lymphocyte-deficient TgH(KL25) mice, which are transgenic for the heavy chain of the lymphocytic choriomeningitis virus (LCMV)-neutralizing monoclonal antibody KL25, mount a focused neutralizing antibody response following...
متن کاملHuman Infection with Lymphocytic Choriomeningitis Virus
Lung contusions and pandemic (H1N1) 2009 can cause ARDS (6,7). We do not know the relative role of each in causing the ARDS that our patient had, but the severity of clinical symptoms, although the lung injury was judged to be only of moderate magnitude, suggests that infl uenza played a major role in the development of his acute lung disease. The infection with oseltamivir-resistant virus, for...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1992
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.66.12.7270-7281.1992